Fatty Acid and Lipotoxicity in Obesity and Diabetes...

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Fatty Acid and Lipotoxicity in Obesity...

Fatty Acid and Lipotoxicity in Obesity and Diabetes (Novartis Foundation Symposium 286)

Name: Fatty Acid and Lipotoxicity in Obesity and Diabetes (Novartis Foundation Symposium 286)
ISBN: 9780470057643

Novartis Foundation

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The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic ? cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle.This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and ? cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.

Категории:

Medicine

Година:

2008

Издание:

Издателство:

Wiley

Език:

english

Страници:

221

ISBN 13: